61.3 kd binding partner gst glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases 786-993

Present Title & Affiliation Primary Appointment Professor, Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX Dual/Joint/Adjunct Appointment Professor, Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX Research Interests My translational research interests are in autophagy, mitochondrial dynamics, epigenetic modulators and MAPK inhibition in AML Clinical Interests My clinical interests are in bringing innovative targeted therapies for the treatment of AML and MDS

Eighteen thematic categories were identified, 10 of which were consistent with expected themes

Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin

Clinical studies have shown that a combination of glycine and N-acetylcysteine reliably increases low glutathione levels and thus reduces oxidative stress