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KuhnHBanthiyaSvan LeyenK.Mammalian lipoxygenases and their biological relevance

Contraindicated in patients with a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia Syndromes (MEN 2) Consult your healthcare provider if you have a history of pancreatitis, as the medication may increase risk Serious side effects may involve hypoglycemia, kidney issues, or allergic reactions 1,5 Not suitable for individuals with type 1 diabetes or diabetic ketoacidosis Medication interactions may occur with those on insulin, oral diabetes medications, oral contraceptives, and blood thinners

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Strikingly, the presence of double bonds in rings A and B, the carbonyl group in position 3 and the side chain in position 17 seem to have a high impact on fragmentation