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2008;135:19451952 Powell EE, Ali A, Clouston AD, Dixon JL, Lincoln DJ, Purdie DM, et al

Cholesterol lowering with bile salt hydrolase-active probiotic bacteria, mechanism of action, clinical evidence, and future direction for heart health applications

10.1016/j.jacl.2020.04.008 25

The IL-22-responsive transcriptional module is significantly enriched in both mouse colitis models and human UC, with elevated levels of neutrophil-active chemokines such as Cxcl1 , Cxcl2 , Cxcl3 , and Cxcl5 [94]