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Obesity: Excess weight can put additional pressure on the rectum

doi: 10.7326/0003-4819-121-12-199412150-00009 7 IOM (2015)

Step therapy: You may also be required to attempt step therapy before Aetna approves coverage for Zepbound

Rather than remembering daily pills, patients receive periodic injectionsoften monthly or biweekly depending on individual needsproviding sustained B12 levels between treatments