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[DOI] [PMC free article] [PubMed] [Google Scholar] Eckenstein F, Thoenen H, 1983

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations

In natural compounds, diosgenin and AP-derived polysaccharides show promise in mitigating ferroptosis and hepatic lipid accumulation, while the small molecule inhibitor GLX351322 combats oxidative damage by upregulating GPX4 [242, 243, 245]