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Finally, various triggers have been linked to thyroid autoimmunity, including prior infections, hepatitis C virus, chronic stress, pregnancy, tobacco and alcohol use, certain medications, and alterations in the intestinal microbiota (Wroska et al., 2024)

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Clinical studies have demonstrated that topical niacinamide improves the appearance of aging facial skin, including reductions in fine lines, wrinkles, yellowing, red blotchiness, and hyperpigmented spots, while also enhancing barrier function

Surveillance data from 2014 to 2024 demonstrated a sustained upward trajectory in NAE reports associated with GLP-1 RAs, peaking in 20232024 (Fig