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This suggests that the co-treatment with ferrous iron again switched the signaling mechanisms and mode of cell death from mitochondrial dysfunction-dependent necrosis after APAP alone to LPO-dominated ferroptosis after APAP + Fe 2+ (Figure 1)

Casillo A, Papa R, Ricciardelli A, Sannino F, Ziaco M, Tilotta M, Selan L, Marino G, Corsaro MM, Tutino ML, Artini M, Parrilli E (2017) Anti-biofilm activity of a long-chain fatty aldehyde from antarctic Pseudoalteromonas haloplanktis TAC125 against Staphylococcus epidermidis biofilm

Towards multidimensional genome annotation

In clinical trials, capsaicin also shows to alleviate uremic conditions in patients with CKD (Makhlough et al., 2010