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Longitudinal analysis from the TEDDY trial of fecal microbes and their metabolites from infancy to T1D-onset has uncovered bacterial imbalances notable for reduced ratios of Firmicutes to Bacteroidetes as well as deficient enteric SCFA (116119)

However, the most significant skin improvements typically result from the weight loss achieved, which reduces systemic inflammation from adipose tissue

Mutant 9 (M9) was designated as the best variant and used for all subsequent assays

[DOI] [PubMed] [Google Scholar] 51.Bonnet L., Karkeni E., Couturier C., Astier J., Defoort C., Svilar L., Tourniaire F., Mounien L., Landrier J.F