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Health Canada approved selumetinib (Koselugo) , the oral MEK1/2 inhibitor developed by Alexion, AstraZeneca Rare Disease, for the treatment of adult patients with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas (PN) on March 9, 2026

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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Chen X., Sun X., Wang C., He H