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Altered Methylation: Preserved SAM for other methylation reactions 5

Mutant mice with SOD2 deficiency (established via targeted deletion of SOD2) deteriorates the outcome of both temporary and permanent middle cerebral artery occlusions (Kim et al., 2002, Murakami et al., 1998)

Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test

DNA methylation refers to the transfer of the methyl group provided by SAM to the 5-position carbon atom of cytosine, catalyzed by methyltransferase (DNMT), to form 5-methylcytosine