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Hcy and MMA accumulation occurs as a result of inactivation of the 2 B 12 -dependent enzymes, methionine synthase and methylmalonyl-CoA mutase, respectively

B12 : A water-soluble vitamin involved in metabolism that assists the body using fat and carbohydrates to create energy and make new protein Methionine: Essential amino acid that enhances fat loss within the liver, neutralizes toxins, and promotes lean muscle gain Inositol : Essential amino acid that plays an important role in regulating metabolic function Choline : Essential nutrient that helps regulate memory, mood, muscle control and other important functions L-Carnitine : amino acid produced by the body thats also found in food and supplements

Young cattle have lower reserves of Vitamin B12 in their liver, making them more susceptible to deficiency

Not all fat tissue responds equally to caloric restriction and exercise