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doi:10.1016/j.exger.2024.112522 About TFA salt Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC)

This would thus reduce the off- site side effects

This is referred to as de novo synthesis of choline

Myocardial ischemia and infarction, cardiomyopathy, extreme pallor and coldness of the skin, metabolic acidosis due to elevated blood lactic acid levels, and renal insufficiency have also been reported