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At 37C, therapeutic antibody binding increases the molecules ability to float within the membrane and - as known from traditional immunology - the antigen/antibody complex tends to accumulate at one pole of the cell

4 Department of Endocrinology, Peoples Hospital of Kashgar, Kashgar, Peoples Republic of China Correspondence: Pan-Xia Wang, Department of Endocrinology, Peoples Hospital of Kashgar, Kashgar, Peoples Republic of China, Email [email protected] Sheng Jiang, Department of Endocrinology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Peoples Republic of China, Email [email protected] Abstract: Diabetic kidney disease (DKD), a major microvascular complication of diabetes, affects 30 40% of patients and is the leading cause of end-stage renal disease

AGE accumulation is also affected by the diet