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Inhibition of mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity

Moreover, this review emphasizes several pivotal aspects of the antioxidant effects of LABs, including the activation of the antioxidant signal pathway, the induction of antioxidative enzymes, the formation of a ROS-binding system, the production of metabolites, the enhancement of intestinal barrier integrity, the activation of the oxidative damage repair system, and the assurance of mitochondrial function

(38) Lipoic acid was shown to inhibit the JNK pathway and IRS-1 serine phosphorylation, thereby improving insulin sensitivity

This cascade of events continues and causes a transition from IR to DM type II [137]