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This difference was achieved without any change in food intake, suggesting the weight loss came from metabolic changes rather than appetite suppression

Silk fibroin has emerged as a promising biomaterial in nanoparticles due to its versatile functionalityhigh mechanical strength, flexibility, low immunogenicity, biodegradability, and biocompatibility (Xiaodan et al., 2016), films (Ma et al., 2025), hydrogels (Kaewchuchuen et al., 2024), powders (Rajkhowa et al., 2012), and micro- or nanoparticles (Roamcharern et al., 2025)enabling broad applications in manufacturing and rational drug delivery design

PLoS Biol 2018;16, e2004663, doi: Pasqualetti, P

Since cells contain DNA, and DNA contains purines, anything that increases the breakdown of cells in the body can lead to more uric acid and gout