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29 Reversal of DOACs using pharmacological agents (idarucizumab or activated prothrombin complex concentrate for dabigatran and andexanet alfa or 4-factor prothrombin complex concentrate for the other DOACs) is indicated in patients undergoing unexpected urgent surgery, or in those experiencing serious and life-threatening bleeding

Receptor-bound targets of selective autophagy use a scaffold protein to activate the atg1 kinase