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What the Preclinical Research Suggests: Laboratory studies using animal models have examined several biological processes: Tendon and Ligament Processes: Rodent studies have demonstrated effects in Achilles tendon injury models, with treated animals showing differences compared to controls in controlled laboratory conditions

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A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons

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However, large Phase 3 combination trials provide extensive safety and effectiveness information

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