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Description

Through several mechanisms, including direct interaction with SUR1 and membrane depolarization, intracellular calcium mobilization, and insulin granule priming modification, EPAC2 activation may promote the exocytosis of insulin granules [55, 56]

Krebs LT, Kramar EA, Hanesworth JM, Sardinia MF, Ball AE, et al

As of this writing: The FDA has not published formal reclassification guidance

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