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Blaya, M

When the mutants were introduced into cells along with an RTA expression vector, the mutation at vSP-1 initiation codon abolished the RTA enhancement activity of T3.0, while the mutant bearing the mutation at the vSP-2 initial codon retained the activity comparable to wild-type T3.0

Expert Opinion Cystoscopy and urodynamic testing are appropriate as part of the diagnostic approach when the IC/BPS diagnosis is in doubt or when information that can be gleaned from cystoscopy is needed to guide therapy

Intermittent deprivation of methionine in the diet significantly enhances tumor sensitivity to ferroptosis and collaborates with PD-1 antibodies to inhibit tumor progression and enhance T-cell-mediated anti-tumor immune response (157)