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Perturbations in oocyte mitochondrial function can disrupt these signaling pathways, thereby indirectly impairing granulosa cell function and follicular homeostasis [51, 52]

By enhancing intracellular hydroperoxides, especially hydrogen peroxide, decreasing reduced glutathione concentration, increasing cysteine oxidation, and activating protein kinases, oxidant stress can enhance the activity of transcription factors, such as the nuclear factor kappa B and activator protein-1, which are involved in the expression of cell surface adhesion molecules, growth factors, immunoreceptors, and cytokines

the atmosphere goes down quite a ways until the pressure squeezes it into something resembling a liquid, and then deeper down there may be a solid core

Li P, Nielsen HM, Mullertz A