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Description

10.1002/ana.21539 Ann

In this study, we aimed to reconstruct 3D biliary system in the bioengineered livers by recellularization of rat primary hepatocytes and liver ductal organoids

PMID: 34012877 Int J Rheum DisMiR-223-3p and miR-22-3p inhibit monosodium urate-induced gouty inflammation by targeting NLRP3

This process is accompanied by the ETC breakdown with the failure to produce the necessary amount of ATP, uncompensated production of ROS and RNS, and breakdown of various molecules, which leads to the loss of mitochondrial and cell integrity, and activation of programmed cell death and necrosis