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277 Abnormal NAD + metabolism in the pathophysiological condition Given the essential regulatory role of NAD + in fundamental physiologies, NAD + metabolic abnormalities contribute to the pathophysiology of various diseases, such as infection, cancers, metabolic diseases, aging and age-associated neurodegeneration disorders

Mol Cell Biochem 254:319326 Vasdev S, Gill V, Parai S, Gadag V (2005) Dietary lipoic acid supplementation attenuates hypertension in Dahl salt sensitive rats