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Abumrad NA, Davidson NO

292, G315G322

Furthermore, it regulated the expression of purinergic receptors (including A2A, A3, P2X4, P2X7, and P2Y1), which are recognized for their significant roles in the inflammatory response associated with DED [77]

Avocados are rich in seven-carbon sugars, primarily D-mannoheptulose and perseitol, with D-mannoheptulose offering protective effects against DM by mimicking caloric restriction, which delays aging and related diseases (459)