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In this context, recent advances in targeting ROS by administration of glutathione or its precursors (N-acetyl-cysteine, NAC), and also IL-1 signaling by administrating Anakinra, a IL-1 Receptor antagonist (IL-1Ra), have been reported to prevent inflammation and/or worse clinical outcome in COVID-19 patients (102108)

When to stop Stop the protocol and contact your provider if you experience persistent redness or swelling at injection sites beyond 72 hours, fever, or any systemic symptom that does not correlate with the expected mild post-injection reaction

10.1016/j.neuropharm.2013.04.024 Neuropharmacology 16 BellantiF.MatteoM.RolloT.De RosarioF.GrecoP.VendemialeG.et al (2013)

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