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A chronically diminished GSH:GSSG ratio in circulating blood is however thought to be a valuable surrogate marker of elevated oxidative stress in conjunction with the appearance of low-molecular oxidation products, such as lipid peroxides and protein or non-protein bound forms of cysteine disulfides in blood plasma (Sies, 1999

For those with significant B12 deficiencies, weekly injections might be necessary initially to replenish levels, followed by monthly maintenance doses

The treatment can replenish vitamin and mineral deficiencies and also improve immune function as part of a preventive approach to health and well-being