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Human TH17 lymphocytes induce blood-brain barrier disruption and central nervous system inflammation

Moreover, studies included in this work are often small (Online Supplementary Table S1 (SM)) and thus underpowered, except some exceptions (Hannon et al., Reference Hannon, Dempster, Mansell, Burrage, Bass, Bohlken and Mill2021), which presents the need to create collaborative efforts allowing meta-analysis of comparable epigenetic data

Co-immunoprecipitation (co-IP) After treatment, the cells were lysed in an ice-cold co-IP buffer containing 20 mM Tris-HCl (pH 8.0), 100 mM NaCl, 1 mM EDTA, and 0.5% NP-40, supplemented with a protease inhibitor cocktail (Roche, Cat

Depending on the type of variants in these genes, the ability to metabolize ethanol varies in individuals and is known to influence an individuals drinking habits and subsequent risk of alcohol dependence ( Table 1 Genes concerning Alcohol Dehydrogenase (ADH) and Aldehyde Dehydrogenase (ALDH)