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Keywords oxidative stress endogenous antioxidants free radicals catalase glutathione 1

Office of Dietary Supplements, National Institutes of Health

As a nonenzymatic antioxidant, CoQ10 directly scavenges free radicals, which reduces oxidative stress in cells, it also aids in the regeneration of other antioxidants such as Vitamin E, ensuring that the body's total antioxidant network remains intact, and it contributes to the integrity and fluidity of cell membranes, which can be impaired by oxidative stress [34]

Both animal experiments and clinical investigations have substantiated the role of MMPs in AD initiation and progression (114119)