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Hypertrophic adipocytes can promote the infiltration of macrophages into adipose tissue, thereby creating a local microenvironment characterized by a pro-inflammatory state, manifested by increased production of various cytokines, including tumor necrosis factor- (TNF-), interleukin-6 (IL-6), and chemokines

Here, we show with genetic approaches that a small subpopulation of endothelial cells inside the intestinal villi of the embryonic mouse, characterized by the expression of endothelial cell-specific molecule 1 (Esm1/endocan), gives rise to arterial endothelium in the intestinal wall but also in the distant mesenteric vasculature

doi: 10.1111/cas.12221 41 UchiyamaYHayasakaTMasakiNWatanabeYMasumotoKNagataTet al

Pomh minimalizovat vliv stresu, ivotnho stylu a vnjch faktor, kter mohou pispt ke strnut a ochabnut pokoky