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in: PubMed | Google Scholar | Published November 24, 2025 - More info Therapeutics blocking PI3K/mTOR complex 1 (mTORC1) are commonly used for tumor treatment, and at times achieve major responses, yet minimal residual disease (MRD) persists, leading to tumor relapse

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The nucleus, as the regulatory center of cell genetics and metabolism, is intricately connected with other cellular compartments, complicating the determination of the exact role of ROS within the nucleus