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Elevated carbon dioxide levels cause cerebral vasodilation, increasing cerebral blood volume and intracranial pressure, which exacerbates brain injury ( Acute exacerbations of COPD Acute exacerbations of COPDdefined as acute worsening of respiratory symptoms beyond daily variability, requiring treatment adjustmentssignificantly impact cognitive function

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Grana Mayne agreed, noting that there is a window of opportunity to make sure smoking cessation programs are easily accessible with adequate resources and few barriers to their use