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PMC 6380351

Cancer genome sequencing revealed widespread genetic heterogeneity and profound genomic instability in advanced tumors, 781 therefore, gene sequencing is necessary for precision medicine, as it can provide more information about gene mutations and is crucial for selecting more effective drugs and dosages

Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling trypanosoma cruzi in macrophages

Using label-free quantitative proteomics analysis, we compared the abundance of more than 2000 shared proteins in senescent, proliferating, and quiescent cells to define a senescent cell-specific proteome, which was then subjected to gene ontology (GO) and biological pathway (Kyoto Encyclopedia for Genes and Genomes (KEGG)) systems-level analysis