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When bacteria develop resistance to antibiotics, they can pass those resistance genes to other bacteria

Similarly, in a murine breast cancer LN metastasis model, the expansion of Treg cells in LNs suppresses NK cell activity leading to breast cancer metastasis in LNs (216)

de S et al

These associations involve chronic endogenous elevation, but they establish the biological plausibility of concern for long-acting exogenous analogues [8]