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Parents and caregivers are taught to embed OT goals into daily routines for example, practising fine motor skills through cooking activities, building sensory tolerance through bathtime play, and targeting gross motor coordination through outdoor games

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Similar variations in Pgp in human epileptics would help explain the existence of patients with medically intractable epilepsy who do not respond to AEDs

Discussion Our results provide evidence that intrastromal implantation of a cell-free bioengineered collagen-based material can be a safe and feasible means to reverse the pathologic corneal thinning and deformation in advanced keratoconus