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The study identified two noteworthy metabolomic markers, tyramine and mucic acid, as relevant to the pathogenesis of both psoriasis and its arthritis subtype (123)

In general, glutamate is synthesized from ammonium and alpha-ketoglutarate (a component of the Krebs Cycle) and is used in the synthesis of proteins, other amino acids, and even other neurotransmitters (such as GABA