This is annoying but not catastrophic
There are many scaffold proteins that are associated along with c-MET receptor and leads to activation of downstream signal transduction pathways that include mitogen-activated protein kinase (MAPK) cascades, extracellular signal-regulated kinase 1 (ERK1) and ERK2, Jun amino-terminal kinases (JNKs) and p38, the phosphoinositide 3-kinaseAkt (PI3KAKT) axis, signal transducer and activator of transcription proteins (STATs), and the nuclear factor-b inhibitor- (ib)nuclear factor-b (NF-b) complex [33]
Supplementation should always be done under medical supervision to prevent masking other issues, such as low folate, which is another vitamin deficiency linked to cancer risk
Treatment strategies may include pain medication, using a spinal brace for support, physical therapy, electronic stimulation of nerves (transcutaneous electrical nerve stimulation), adjusting nerve signals (neuromodulation), injections of anti-inflammatory steroids into the spine (epidural steroid injection), inserting a small device between the spine bones (interspinous spacer), and surgical procedures to relieve pressure on the spinal cord (surgical decompression)