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INDICATIONS AND USAGE Cyanocobalamin is indicated for vitamin B 12 deficiencies due to malabsorption, which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency Cyanocobalamin Injection, USP is also suitable for the vitamin B 12 absorption test (Schilling test)

Endogenous BDNF has also been demonstrated to colocalize with ADAP1 in both the soma and the dendrites of primary culture hippocampal neurons, suggesting a role for ADAP1 in regulating BDNF trafficking [118]

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Source: FDA Advisory Committee Calendar, meeting July 23-24, 2026