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Principal component analysis (PCA) was used for unsupervised exploration and visualization of clustering patterns [27]

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The difference is that while cholera enterotoxin causes pathologic changes in intestinal permeability, larazotide improves intestinal permeability and helps to reduce the immune response that occurs when the intestinal membrane is too permeable causing small molecules such as gluten to cross the protective membrane into the blood stream increased membrane permeability or hyperpermeability of the intestinal membrane