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The study emphasizes that specific PKC isozymes, triggered by lipid metabolites and hyperglycemia, contribute to vascular abnormalities such as fibrosis, dysfunction of endothelial and vascular smooth muscle cells (VSMC), monocyte activation, cytokine imbalance, excessive extracellular ROS production, and impaired vascular insulin signaling that contribute significantly to DM associated vascular dysfunction [48]

Eryptosis is characterized by the exposure of PS on the membranes of RBCs, facilitating their clearance from circulation and contributing to anemia in both treated and untreated LC patients

The results are presented as mean of 35 different experiments

Under normal circumstances, peroxisomes maintain the balance between oxidative and antioxidant systems within cells to protect neurons