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Notably, CagriSema is the only one of the three that brings in the amylin system the others stay within the incretin/glucagon family

If you have a history of allergic or hypersensitivity reactions from any ingredient of semaglutide or glycine, you should not use this combination, as it may trigger hypersensitivity reactions again

Dosage depends on the severity of symptoms and other personal factors

Intranasal administration, though less studied with Dihexa specifically, would theoretically provide the most direct CNS delivery with minimal systemic exposurepotentially requiring even less frequent dosing to maintain effective brain tissue concentrations