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doi: 10.1016/j.envint.2020.105887

These changes occurred before the increase in THDA levels, indicating that the loss of BDNF-TrkB signalling and upregulation of GSTO2 happens before the hyperdopaminergic state, as with the Trkb Penk -KO mice, supporting that GSTO2 increase is more likely a cause of neurodegeneration than a consequence of it