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there is a lack of large, independent, randomised controlled trials with a control group

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

The honest answer is that it depends on the indication, and the timeline varies enough between tissue types that a single number is misleading

380 Firstly, the expression of GLP-1R is enhanced in the inflamed muscle fibers under pathological conditions, revealing the critical role of GLP-1R in regulating the muscles response to inflammation