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Front Pharmacol 15:1367848 Pinto YM, Elliott PM, Arbustini E, Adler Y, Anastasakis A, Bhm M, Duboc D, Gimeno J, de Groote P, Imazio M, Heymans S, Klingel K, Komajda M, Limongelli G, Linhart A, Mogensen J, Moon J, Pieper PG, Seferovic PM, Schueler S, Zamorano JL, Caforio AL, Charron P (2016) Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases

Researchers across gastroenterology, orthopaedics, neuroscience, and pharmacology have explored the compound's interaction with multiple biological pathways

Studies show less than 10% reaches systemic circulation due to degradation by peptidases in the small intestine