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some BPC-157 investigations Rabbits Employed in orthopedic research primarily for BPC-157 Dogs Limited cardiovascular studies for both peptides Cell culture Fibroblasts, endothelial cells, keratinocytes, various tissue-specific lines Human studies NONE for the combination

4.4.2 Function of curcumin in HD Although multiple cellular events, including oxidative stress, mitochondrial dysfunction, neuroinflammation and transcriptional dysregulation, have been identified in HD, the development of effective therapies with favorable safety profiles remains an unmet medical need (Elifani et al., 2016)