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Sensitivities of nociceptive neurons to heat stimulation and TRPV1 activation were increased by the activation of PKC and inflammatory mediators (Khasar et al., Inflammation: Brain and spinal glia neurons have a main role on homeostasis in central nervous system and peripheral nervous system

In order to address the issue of therapeutic resistance driven by reprogramming of tumor glutamine metabolism, future studies must thoroughly examine the heterogeneity of glutamine dependence in different genetic backgrounds (e.g., KRAS-mutant vs

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