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The CPT 96372 modifier rules aren't complicated once you understand the logic behind them, but they do require knowing which modifier applies to which code on the claim

A natural decline occurs over time in the levels of collagen, with production of new collagen decreasing and existing collagen reducing structural and functional integrity

Proper storage and handling procedures are important for maintaining product purity, consistency, and reliability throughout laboratory applications

A baseline IGF-1 already at or above the age-appropriate reference range is also a reason to hold: the goal is to support a declining axis, not push one that is already at the top of normal