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Vitamin B 12 synthesis by human small intestinal bacteria [La sntesis de la vitamina B 12 por pequeas bactierias intestinales en humanos]

These pain-relieving effects are blocked by drugs that affect norepinephrine, but not serotonin, suggesting that the pain relief works through adrenergic pathways (9)

The formation of 5-methylTHF depends on N 5,10 -methylenetetrahydrofolate reductase (MTHFR), which catalyzes the reduction of N 5,10 -methylenetetrahydrofolate (5, 10-methyleneTHF) (Fig