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Q5: Does AOD-9604 raise IGF-1 or blood sugar

We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)

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As shown in Table 1 and Figure 6, such inhibitors mainly include MvH45 (Van Haren et al., 2017), AK-12 (Ruf et al., 2022), MS2756 (Babault et al., 2018), MS2734 (Babault et al., 2018), GYZ-78 (Gao et al., 2019), NS1 (Kuzmi et al., 2021), LL320 (Chen D