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doi: 10.1016/j.bbalip.2018.12.005

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The interaction between MDSCs and TAMs is particularly significant, as it drives the polarization of macrophages toward an anti-inflammatory M2 phenotype, supporting tumor growth while suppressing cytotoxic immune responses

006852, The Jackson Laboratories) mice were used for in vitro circadian synchronization experiments

This elevated free amino acids pool under NP treatment suggests enhanced nitrogen turnover and possible redirection toward metabolic and osmoprotective pathways, including secondary metabolite biosynthesis