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Dymek, M., Olechowska, K., Hc-Wydro, K., & Sikora, E

Inform patients to contact their care team if changes in vision are experienced during treatment

Non-medication approaches include: Engaging in physical activity such as strength training, cardio, stretching, or water-based exercisea healthcare provider can recommend the type of exercise that may work best for you Using a mobility aid such as a walking stick or knee or foot braces Applying heat or cold to the painful joints Non-steroidal anti-inflammatory drugs (NSAIDs)such as Advil (ibuprofen) or Aleve (naproxen)are typically the first recommended pain relievers

Fumarate Fumarate is another example of an oncometabolite produced by the action of fumarate hydratase on succinate