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Our previous studies revealed the essential role of HGF in mechano-biology of postnatal muscle growth and regeneration centered on resident myogenic stem satellite cells, which are positioned between the basal lamina and the sarcolemma of postnatal myofibers and normally found in a mitotically and metabolically quiescent or near-dormant state (protracted G 1 phase, also referred to G 0 ) in adult muscle

The functional medicine investigation of tinnitus often uncovers overlapping drivers: gut dysbiosis and intestinal permeability affecting systemic inflammation, MTHFR and methylation impairment disrupting neurotransmitter synthesis, and cognitive and mood dysregulation amplifying central sensitisation to auditory signals